Our Mission

At the McRae Lab, we combine structural biology, RNA engineering, and synthetic biology to design functional RNA nanostructures for therapeutic and biomedical applications. By integrating cryogenic electron microscopy with computational design and molecular biology, we aim to decode and reprogram the structural rules that govern RNA folding and function. Our work seeks to expand the toolkit for RNA-based therapeutics, with a focus on stability, specificity, and modular design, ultimately enabling next-generation treatments that are programmable at the molecular level.